The things to do now before we can get our hands on SharePoint 2010 is to check our current platform.
If your current sharepoint have service pack 2 installed then you can use the following command to check your current deployment and see if its ready for the
upcoming sharepoint 2010. Use the following command at command line to check the readiness
stsadm -o preupgradecheck
In the end it will create a report for you to verify your deployment.
Few important ones are
Sharepoint 2010 DOES NOT support 32 bit platform!
Use *.wsp as much you can for your deployments
Read best practices for sharepoint and try using them as much as you can.